Tackling drug resistance
 There was a time around the middle of the last century when it seemed  that humans could decisively vanquish the microbes that caused so many  dreadful, often deadly, diseases. But that sense of victory over an  enemy has given way to alarm. Drug-resistant pathogens have sprung up  and ‘superbugs' that can shrug off most drugs that are thrown at them  have surfaced and spread across the world. With few new antimicrobials  under development, there is a real sense among medical experts of  humanity having its back to the wall and of the frightening possibility  of a return to the bad old days when what started as a simple infection  could get completely out of control. This year's World Health Day (April  7) focusses on antimicrobial resistance and its global spread. In a  highly interconnected world, drug-resistant microbes can leap from one  country to another. Last year, there was a furore over the spread of  highly drug-resistant bacteria, which had the New Delhi  metallo-beta-lactamase (NDM-1) gene, from South Asia to several  countries. But ‘superbugs' have made their way to India from elsewhere  in the world too. For instance, studies of methicillin-resistant Staphylococcus aureus (MRSA)  bacteria isolated in India have indicated a movement of such organisms  from the United States, Europe, and Australia to this country. 
 In India, as in other countries, such dangerous microbes are circulating  not only in hospitals but also in the larger community; poor sanitation  and faecal contamination of water supplies have allowed some highly  antibiotic-resistant bacteria to spread. Drug-resistance is a major  issue in tuberculosis. India accounts for one-fifth of the global burden  of the disease and two people die of it every three minutes. The rise  of resistance as a natural consequence of the process of evolution is  perhaps inevitable. But the misuse of antibiotics greatly hastens this  process. There is a great deal that can and must be done to conserve the  drugs that are available and still effective. Over-the-counter sales of  antibiotics must be stopped. Physicians need to be educated on when it  is appropriate to use antibiotics. Even when an antibiotic is needed, it  is essential that the right drug is given at an adequate dosage and for  a suitable duration. A proper system of surveillance for antimicrobial  resistance as well as regularly updated guidelines for treatment would  help doctors make the right choices. Further, the use of antibiotics as  growth-promoters in livestock needs to be curtailed. In all of this, the  government, the medical fraternity, and the public must play their  part. 
Changing an established order
 The international monetary system has been in need of fundamental  reform. It is dominated by dollar holdings, with the American currency  remaining the world's principal reserve currency as well as the most  widely used in private transactions. The dollar, which faced many  challenges, has remained supreme mainly for want of an alternative. A  recent G20 seminar held in Nanjing, China, ended without any consensus  on international monetary reform. The stasis is unfortunate. The system  may not have caused the recent global imbalances or current instability  in the global economy, but it has certainly been ineffective in  addressing them. First, it has created a global recessionary bias both  during and after financial crises. Secondly, there is a certain amount  of tension in using a national currency as a reserve. The U.S. has been  running huge budgetary and current account deficits. Should it succeed  in reining in the deficits, global liquidity would shrink. Thirdly, the  system has encouraged large dollar accumulations by several countries by  way of “self-insurance” against future crisis. The very large dollar  holdings by China and some other countries have added to global  imbalances. 
 Various attempts at identifying alternative reserve currencies have  floundered. The euro seemed promising at one time but the current debt  problems in some euro zone countries have raised doubts over its long  term suitability. Given the strength of China, the yuan is bound to  become an important reserve currency in course of time, freely  convertible and with an exchange rate mirroring its growing clout. Some  out-of-the-box solutions are required. Nobel laureate Joseph Stiglitz  has, in a recent article in the Financial Times, suggested that  the SDRs issued by the International Monetary Fund should play a greater  role in the international monetary system. SDRs, which are strictly the  IMF's unit of account, represent a potential claim on other countries'  freely usable currency reserves, for which they can be exchanged  voluntarily. The specific proposal is to issue a significant amount (up  to $390 billion) of new SDRs every year for the next three years.  Central banks can exchange the SDRs for hard currency and use it to  finance imports. The inherent recessionary bias in the existing system  is thus avoided. Being relatively small, the new issues will not  accentuate global imbalances. The effectiveness of the SDRs ought to be  enhanced through a variety of measures, which are inextricably linked to  IMF reform. The medium-term goal is to make SDRs the main, or even the  only, means of IMF financing. The dollar's pre-eminence in private trade  and remittances will remain unaffected. 

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